Unsubstituted Phenols
Medchemexpress LLC HY-N0792 5mg Medchemexpress, Tectorigenin CAS:548-77-6 Purity:>98%
Medchemexpress, HY-N0792 5mg Tectorigenin CAS:548-77-6 Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsonii Benth. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0377 5mg Medchemexpress, Liquiritigenin CAS:578-86-9 Purity:>98%
Medchemexpress, HY-N0377 5mg Liquiritigenin CAS:578-86-9 Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β ( ERβ ) agonist with an EC 50 of 36.5 nM for activation of the ERE tk-Luc. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0339 100mg Medchemexpress, Syringic acid CAS:530-57-4 Purity:>98%
Medchemexpress, HY-N0339 100mg Syringic acid CAS:530-57-4 Syringic acid is correlated with high antioxidant activity and inhibition of LDL oxidation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0767 1mg Medchemexpress, Isoorientin CAS:4261-42-1 Purity:>98%
Medchemexpress, HY-N0767 1mg Isoorientin CAS:4261-42-1 Isoorientin is a potent inhibitor of COX-2 with an IC 50 value of 39 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0897 5mg Medchemexpress, Corylifol A CAS:775351-88-7 Purity:>98%
Medchemexpress, HY-N0897 5mg Corylifol A CAS:775351-88-7 Corylifol A inhibits IL-6-induced STAT3 activation and phosphorylation, with an IC 50 of 0.81 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Ko 143 | 461054-93-3 | MFCD19053160 | 99.9% | 469.57 g·mol⁻¹ | C26H35N3O5 | 50 MG
Ko 143 is a potent, selective inhibitor of the ATP-binding cassette subfamily G member 2 (ABCG2/BCRP) used as a research reagent to investigate transporter-mediated drug efflux and multidrug resistance. It exhibits nanomolar activity in biochemical and cell-based assays and shows substantial selectivity versus other transporters. Supplied as a research-grade small molecule for laboratory use only.
- Potent ABCG2 inhibition at nanomolar concentrations.
- High selectivity over P-gp and MRP-1.
- Suitable for studies of transporter activity and drug resistance.
- Supplied in milligram quantities for laboratory experiments.
- Stable as powder when stored appropriately at low temperature.
Medchemexpress LLC Ko 143 | 461054-93-3 | MFCD19053160 | 100.0% | 469.6 g/mol | C26H35N3O5 | 1 ML
Potent, selective ABCG2 (BCRP) inhibitor used to probe transporter function and multidrug resistance. Shows over 200-fold selectivity versus P-gp and MRP-1; supplied as a 10 mM solution in 1 mL for laboratory use.
- Potent and selective ABCG2 (BCRP) inhibitor for transporter studies.
- Displays greater than 200-fold selectivity over P-gp and MRP-1.
- Supplied as a 10 mM solution in 1 mL for convenient dosing.
- Molecular weight 469.6 g/mol and formula C26H35N3O5.
- CAS number 461054-93-3 for unambiguous identification.
Medchemexpress LLC Nα,Nα-bis(carboxymethyl)-L-lysine | 113231-05-3 | MFCD00237437 | 98.8% | 262.26 | C10H18N2O6 | 10 G
Nα,Nα-Bis(carboxymethyl)-L-lysine is a research-grade small molecule that competitively inhibits the bitter taste receptor T2R4, with a reported IC50 of approximately 59 nM. It is used in receptor pharmacology and cell-based assays to probe T2R4-mediated signaling; in vitro studies show reduction of basal receptor activity, while limited in vivo effects on bitter taste behavior have been reported.
- Competitive inhibitor of bitter taste receptor 4 (IC50 ≈59 nM).
- Suitable for receptor pharmacology and cell-based assays.
- Shown in vitro to reduce basal activity of constitutively active T2R4 mutants.
- Reported minimal in vivo effect on bitter taste licking behavior at 10 μM.
- High purity material (98.8%) for research use.
- Molecular weight 262.26; formula C10H18N2O6.
Medchemexpress LLC HY-N0233 5mg Medchemexpress, Bavachin CAS:19879-32-4 Purity:>98%
Medchemexpress, HY-N0233 5mg Bavachin CAS:19879-32-4 Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC 50 s of 320 and 680 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
ILEX LIFE SCIENCES LLC TRYPSIN/EDTA P10-020500 500ML
PAN-Biotech Trypsin 0.25% / EDTA 0.02% in DPBS, w/o: Ca and Mg (500 ml). DESCRIPTION: PAN-Biotech Trypsin 0.25% / EDTA 0.02% in PBS, w/o: Ca and Mg is a porcine pancreas-derived enzyme plus EDTA in a PBS solution. Trypsin-EDTA solution is commonly used for the dissociation of anchorage-dependent (adherent) mammalian cells and tissues from culture surfaces. The concentration of trypsin necessary to dislodge cells from their substrate is dependent on the cell type and the age of the culture. Ethylenediaminetetraacetic acid (EDTA), a chelating agent, is often added to trypsin solutions to enhance enzymatic activity by neutralizing calcium and magnesium ions that enhance cell-to-cell adhesion and obscure the peptide bonds on which trypsin acts. LIQUID/POWDER: Liquid. PHENOL RED: Without Phenol Red. Ca/Mg CONTENT: Without Ca and Mg. TRYPSIN: 0.25% Trypsin. EDTA: 0.02% EDTA. STERILE: Yes. STORAGE TEMP.: -20°C. MANUFACTURER: PAN-Biotech GmbH (Germany).
Medchemexpress LLC Procyanidin B3 | 23567-23-9 | 5 MG
Procyanidin B3 is a natural product that exhibits antioxidant activity and oral bioavailability. It has good blood-brain barrier penetration and acts as a selective inhibitor of histone acetyltransferase (HAT). It inhibits p300 HAT-mediated acetylation of the androgen receptor and can alleviate intervertebral disc degeneration (IVDD) by inhibiting the formation of the TLR4/MD-2 complex. Procyanidin B3 is suitable for research related to prostate cancer and arthritis.
- Natural product
- Antioxidant activity
- Oral bioavailability
- Good blood-brain barrier penetration
- Selective inhibitor of histone acetyltransferase (HAT)
- Inhibits p300 HAT-mediated acetylation of the androgen receptor
- Alleviates intervertebral disc degeneration (IVDD) by inhibiting the formation of the TLR4/MD-2 complex
- Can be used in research on prostate cancer and arthritis
Medchemexpress LLC Kuwanon E | 68401-05-8 | 5 MG
Kuwanon E is a flavonoid isolated from Morus alba.
- Cytotoxic to human monocytic leukemic cell lines.
- Reduces the level of IL-1β.
- Shows cytotoxic activity against THP-1 human monocytic leukemic cell line, with an IC50 of 4.0±0.08 μM.
- Inhibits SERCA1 in New Zealand rabbit skeletal muscle SR vesicles.